ERCC-3 (excision repair cross-complementing rodent repair deficiency, complementation group 3)
نویسندگان
چکیده
منابع مشابه
Predictive value of excision repair cross-complementing rodent repair deficiency complementation group 1 and ovarian cancer risk.
OBJECTIVE We aimed to analyze the association between excision repair cross-complementing rodent repair deficiency complementation group 1 (XRCC1) and ovarian cancer risk. METHODS We performed a hospital-based case-control study with 155 cases and 313 controls in China. All Chinese cases with newly diagnosed primary ovarian cancer between May 2005 to May 2010 in our hospital were invited to p...
متن کاملERCC 1 ( excision repair complementing defective repair in Chinese hamster )
ERCC1 is expressed at higher levels in tumor tissue compared to normal tissue and the expression shows more inter-individual variation among cancer patients than among healthy individuals. ERCC1 expression and ERCC1 protein levels in tumor tissue may predict response to chemotherapy. Thus, non-small cell lung cancer patients with undetectable ERCC1 protein levels in tumor tissue had a longer su...
متن کاملIdentification of the Eleventh Complementation Group of UV-sensitive Excision Repair-defective Rodent Mutants I
The drug-sensitive mutant UVS1, isolated from the Chinese hamster cell line CHO9, was previously found to complement the UV sensitivity of the excision repair-defective rodent mutants representative of groups 1 to 8 (Hata et al., Cancer Res., 51: 195-198, 1991; M. Numata et aL, personal communication). Recently two new complementation groups of UV-sensitive CHO mutants, e.g., groups 9 and 10, h...
متن کاملX-ray repair cross-complementing group 3 common polymorphism is not associated with cervical cancer risk
Recently, some reports investigated the association between X-ray Repair Cross-Complementing group 3 (XRCC3) and cervical cancer risk. However, the results were inconclusive. The meta-analysis, thus, assessed whether XRCC3 T241M polymorphism was associated with cervical cancer risk. Odds Ratios (ORs) with 95% Confidence Intervals (CIs) were calculated. Five case-control studies with a total of ...
متن کاملX-Ray Repair Cross Complementing Protein 1 in Base Excision Repair
X-ray Repair Cross Complementing protein 1 (XRCC1) acts as a scaffolding protein in the converging base excision repair (BER) and single strand break repair (SSBR) pathways. XRCC1 also interacts with itself and rapidly accumulates at sites of DNA damage. XRCC1 can thus mediate the assembly of large multiprotein DNA repair complexes as well as facilitate the recruitment of DNA repair proteins to...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/37723